What are the Nutritional Supplements to Treat Hair Loss


Hot subjects in the therapy of alopecia areata were discussed in Mesinkovska's presentation, including vaccinations and viruses, JAK inhibitors, dupilumab, minoxidil, and what is in the works.

The association between alopecia areata and COVID-19, as well as the COVID-19 vaccine and boosters, were the topics of Mesinkovska's opening remarks. In other instances, many of Mesinkovska's patients developed moderate COVID-19 cases followed by alopecia areata totalis. Additionally, after receiving the COVID-19 vaccination, several patients with alopecia areata who had previously been stable or making progress started losing their hair once more. Mesinkovska emphasized that while she does not think this should be a justification for forgoing a COVID-19 vaccination or booster, physicians should take the side effects into consideration and discuss them with their patients.

For the treatment of adult alopecia areata, doctors now have a new JAK inhibitor to choose from: baricitinib (Olumiant; Eli Lily). Clinical trials for deuruxolitinibCTP 543, ritlecitinib, and delgotcitinib are now being conducted for alopecia areata. Mesinkovska advised doctors to address adverse occurrences with their patients and to be aware of the black box warnings for JAK inhibitors.

Dupilumab also has promising potential as a therapy for alopecia areata. IL-4 and IL-13 antagonist dupilumab is presently licensed to treat both adult and pediatric atopic dermatitis. For individuals with alopecia areata who are hesitant to begin JAK inhibitors or for young patients, minoxidil is still an effective treatment choice. Minoxidil side effects include lower limb edema, postural hypotension, and hypertrichosis.

Finally, the sphingosine 1-phosphate receptor modulator etrasimod is a potential treatment for alopecia areata. It is a once-daily oral pill with a history of eosinophilic esophagitis, Crohn's disease, and ulcerative colitis.

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