Rare Diseases

Hot subjects in the therapy of alopecia areata were discussed in Mesinkovska's presentation, including vaccinations and viruses, JAK inhibitors, dupilumab, minoxidil, and what is in the works. The association between alopecia areata and COVID-19, as well as the COVID-19 vaccine and boosters, were the topics of Mesinkovska's opening remarks. In other instances, many of Mesinkovska's patients developed moderate COVID-19 cases followed by alopecia areata totalis. Additionally, after receiving the COVID-19 vaccination, several patients with alopecia areata who had previously been stable or making progress started losing their hair once more. Mesinkovska emphasized that while she does not think this should be a justification for forgoing a COVID-19 vaccination or booster, physicians should take the side effects into consideration and discuss them with their patients. For the treatment of adult alopecia areata, doctors now have a new JAK inhibitor to choose from: baricitini

Rare oral abnormalities are diseases and dysfunctions of the oral tissues and dentition produced by faulty genes. Many hereditary oral diseases are symptoms of more complex disorders and are caused by inherited features and abnormalities or by spontaneous genetic mutations. Appropriate skeletal and teeth formation necessitates the integration of multiple mechanisms beginning in early embryonic development. Patterning of the head, limbs, and dental parts, cell migration and expansion, differentiation to specialised cells, matrix secretion, bio mineralization of bones and teeth, and bone remodelling are examples of these. Types of Rare Oral Diseases 1. Hyperdontia :  This uncommon disorder affects around 2% of the population. However, in some situations, a person will develop extra teeth, a disease known as hyperdontia. Hyperdontia patients often have only one extra tooth, which is commonly positioned behind the top, front teeth. This disorder is assumed to be inherited, however it